Iontophoresis using specially designed current, can
give about 400 % better penetration compared to simple topical
application. This is opening up a major field for rejuvenation of the
skin.
Iontophoresis has made it possible to achieve
results, which we could never achieve before. An example is scarring
from acne or chicken pox. Dermabrasions were never very effective but
this was the best that we had. Now we can use iontophoresis to get
even better results. However, the problem with iontophoresis is that
it only works if the molecule can be ionised into positive and
negative charged components. This is not an impediment for
sonophoresis, which is the use of sound waves to drive chemicals into
the skin by changing the barrier qualities of skin. Sonophoresis is
also becoming refined and we will no doubt see more effective
treatments resulting from sonophoresis.
By sonophoresis, I do not mean ultrasound.
Ultrasound uses frequencies about 50 times higher than the upper limit
of human hearing. It is not as effective as iontophoresis.
Sonophoresis, on the other hand, is at the upper level of human
hearing and is far more effective. Up to 4000% better penetration can
be achieved within 5 minutes compared to simple topical application.
At this stage there is only one machine that offers sonophoresis like
this, the Environ® Ionzyme machine which incorporates both
iontophoresis and sonophoresis.
This combination offers us opportunities to restore
youth to photodamaged skin to a degree previously considered
impossible. I predict that within a few years, peeling will become
less important and the major changes in skin will be done by enhanced
delivery systems
Unfortunately, the treatments do take time and these results can
only achieved if the frequency of treatment is radically increased to
at least twice a week for about 24 treatments. Of course, the result
has to be maintained by periodic treatments. When one examines skin
treated by these modalities with a microscope, the epidermis has been
demonstrated to be between 30 to even 100% thicker after the
treatment. The important keratinocytes become much more normal,
pigmentation is reduced and a thicker layer of collagen is laid down
in the upper dermis.
Summary:
For established photodamage and scarring, we have to rely on
intensive treatments to make the skin smoother, lighter and more
radiant. Newer treatments are being developed which have scientific
validity and give both visual and clinical evidence of improvement to
a degree that has never before been achieved by simple topical
treatments.